| ncRNA name | hsa-miR-4480 |
| ncRNA Category | miRNA |
| Disease name | age-related macular degeneration (AMD) |
| Species | Homo sapiens |
| Tissues/Cell_line | human RPE cell line ARPE-19 |
| Methods | genotyping, luciferase reporter assay, RNA Electrophoretic Mobility Shift assay (RNA EMSA) |
| Expression pattern | associated |
| Functional description | Our data suggest that rs7747909 in IL-17A may be associated with development of AMD in a Caucasian cohort and that this SNP can alter the ability of hsa-miR-4480 to bind and degrade IL-17A mRNA in vitro. |
| PubMed ID | 26765636 |
| Year | 2016 |
| Title | Functional single nucleotide polymorphism in IL-17A 3' untranslated region is targeted by miR-4480 in vitro and may be associated with age-related macular degeneration. |
| Drug-related ncRNA | NO |
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